I hear this question all the time in the fitness world. Honestly there is no one specific “best way” to loose weight. Each client will respond differently to a training program, however I think the basic principles you need to include during a weight loss program are cardio + resistance + nutrition + Sleep . A combination of these four things creates a fat burning machine. Cardio gets your heart rate up and helps you burn more calories. Resistance and or strength training helps you gain muscle, more muscle leads to greater caloric expenditure during everyday activities. Nutrition is the key factor when it comes to weight loss because the number one rule for weight loss is to have a calorie deficit, simply meaning to use more calories in a day then you consume. When you combine these four basic fitness techniques you should see great results.
Disclaimer: I am not a doctor or licensed dietitian. Please contact your physician to make sure this is right for you. I also do not have any affiliations with the link provided